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Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation
Based on the investigation of neprilysin (NEP) regulation in a translational porcine model of chronic heart failure (HF), this study concluded: 1) that kidneys might play a crucial part in systemic NEP regulation based on 20 to 100 higher NEP content and/or activity compared with any other organ; 2)...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393434/ https://www.ncbi.nlm.nih.gov/pubmed/32760858 http://dx.doi.org/10.1016/j.jacbts.2020.05.011 |