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ω-6 Polyunsaturated fatty acids (linoleic acid) activate both autophagy and antioxidation in a synergistic feedback loop via TOR-dependent and TOR-independent signaling pathways

ω-6 Polyunsaturated fatty acids (PUFAs) are essential fatty acids that participate in macroautophagy (hereafter referred to as autophagy) and the Kelch ECH-associating protein 1 (Keap1)—nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant system in organisms. However, the molecular mechani...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Zhou, Yan, Wu, Mengjiao, Li, Xueshan, Mai, Kangsen, Ai, Qinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393504/
https://www.ncbi.nlm.nih.gov/pubmed/32732901
http://dx.doi.org/10.1038/s41419-020-02750-0