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IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b

Bone marrow mesenchymal stem cells (MSCs) have demonstrated therapeutic effects for colitis through immunomodulation and anti-inflammation. However, whether MSC-derived exosomes possessed the similar function remains unclear. In present study, exosomes were isolated from control and IFN-γ-primed MSC...

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Detalles Bibliográficos
Autores principales: Yang, Ruili, Huang, Huaming, Cui, Shengjie, Zhou, Yikun, Zhang, Ting, Zhou, Yanheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393506/
https://www.ncbi.nlm.nih.gov/pubmed/32733020
http://dx.doi.org/10.1038/s41419-020-02788-0