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Ocular Hypertension Drives Remodeling of AMPA Receptors in Select Populations of Retinal Ganglion Cells

AMPA-type glutamate receptors in the CNS are normally impermeable to Ca(2+), but the aberrant expression of Ca(2+)-permeable AMPA receptors (CP-AMPARs) occurs in pathological conditions such as ischemia or epilepsy, or degenerative diseases such as ALS. Here, we show that select populations of retin...

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Detalles Bibliográficos
Autores principales: Sladek, Asia L., Nawy, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393603/
https://www.ncbi.nlm.nih.gov/pubmed/32792936
http://dx.doi.org/10.3389/fnsyn.2020.00030