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ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data

BACKGROUND: To identify the association between somatic ataxia-telangiectasia mutated (ATM) mutations and improved radio-sensitivity, we retrospectively reviewed next-generation sequencing data from patients diagnosed with isocitrate dehydrogenase (IDH)-wildtype high-grade glioma. METHODS: We includ...

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Detalles Bibliográficos
Autores principales: Kim, Nalee, Kim, Se Hoon, Kang, Seok-Gu, Moon, Ju Hyung, Cho, Jaeho, Suh, Chang-Ok, In Yoon, Hong, Chang, Jong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393839/
https://www.ncbi.nlm.nih.gov/pubmed/32736562
http://dx.doi.org/10.1186/s13014-020-01619-y