Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

BACKGROUND: Neuronal damage in acute CNS injuries and chronic neurodegenerative diseases is invariably accompanied by an astrocyte reaction in both mice and humans. However, whether and how the nature of the CNS insult—acute versus chronic—influences the astrocyte response, and whether astrocyte tra...

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Detalles Bibliográficos
Autores principales: Das, Sudeshna, Li, Zhaozhi, Noori, Ayush, Hyman, Bradley T., Serrano-Pozo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393869/
https://www.ncbi.nlm.nih.gov/pubmed/32736565
http://dx.doi.org/10.1186/s12974-020-01898-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393869/
https://www.ncbi.nlm.nih.gov/pubmed/32736565
http://dx.doi.org/10.1186/s12974-020-01898-y

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