Dioscin Promotes Prostate Cancer Cell Apoptosis and Inhibits Cell Invasion by Increasing SHP1 Phosphorylation and Suppressing the Subsequent MAPK Signaling Pathway

Dioscin possesses antioxidant effects and has anticancer ability in many solid tumors including prostate cancer (PCa). Nevertheless, its effect and mechanism of anti-PCa action remain unclear. The tyrosine protein phosphatase SHP1, which contains an oxidation-sensitive domain, has been confirmed as...

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Detalles Bibliográficos
Autores principales: He, Shuyun, Yang, Jinrui, Hong, Shaobo, Huang, Haijian, Zhu, Qingguo, Ye, Liefu, Li, Tao, Zhang, Xing, Wei, Yongbao, Gao, Yunliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394018/
https://www.ncbi.nlm.nih.gov/pubmed/32792945
http://dx.doi.org/10.3389/fphar.2020.01099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394018/
https://www.ncbi.nlm.nih.gov/pubmed/32792945
http://dx.doi.org/10.3389/fphar.2020.01099

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