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Monitoring of Early Changes of Circulating Tumor DNA in the Plasma of Rectal Cancer Patients Receiving Neoadjuvant Concomitant Chemoradiotherapy: Evaluation for Prognosis and Prediction of Therapeutic Response

Introduction: Patients with locally advanced rectal cancer (LARC) are undergoing neoadjuvant chemoradiotherapy (NCRT) prior to surgery. Although in some patients the NCRT is known to prevent local recurrence, it is also accompanied by side effects. Accordingly, there is an unmet need to identify pre...

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Detalles Bibliográficos
Autores principales: Pazdirek, Filip, Minarik, Marek, Benesova, Lucie, Halkova, Tereza, Belsanova, Barbora, Macek, Milan, Stepanek, Lubomír, Hoch, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394215/
https://www.ncbi.nlm.nih.gov/pubmed/32793464
http://dx.doi.org/10.3389/fonc.2020.01028