Cargando…

Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct hsdS Specificity Genes That Can Switch System Specificity by Recombination

N(6)-Adenine DNA methyltransferases associated with some Type I and Type III restriction-modification (R-M) systems are able to undergo phase variation, randomly switching expression ON or OFF by varying the length of locus-encoded simple sequence repeats (SSRs). This variation of methyltransferase...

Descripción completa

Detalles Bibliográficos
Autores principales: Atack, John M., Guo, Chengying, Litfin, Thomas, Yang, Long, Blackall, Patrick J., Zhou, Yaoqi, Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394358/
https://www.ncbi.nlm.nih.gov/pubmed/32723795
http://dx.doi.org/10.1128/mSystems.00497-20