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Delayed short-term tamoxifen treatment does not promote remyelination or neuron sparing after spinal cord injury

The tamoxifen-dependent Cre/lox system in transgenic mice has become an important research tool across all scientific disciplines for manipulating gene expression in specific cell types. In these mouse models, Cre-recombination is not induced until tamoxifen is administered, which allows researchers...

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Detalles Bibliográficos
Autores principales: Pukos, Nicole, McTigue, Dana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394399/
https://www.ncbi.nlm.nih.gov/pubmed/32735618
http://dx.doi.org/10.1371/journal.pone.0235232