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The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres

Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular protein, the promyelocytic leukemia protein (...

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Detalles Bibliográficos
Autores principales: Collin, Vanessa, Gravel, Annie, Kaufer, Benedikt B., Flamand, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394443/
https://www.ncbi.nlm.nih.gov/pubmed/32658923
http://dx.doi.org/10.1371/journal.ppat.1008683