Cargando…
The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres
Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular protein, the promyelocytic leukemia protein (...
Autores principales: | Collin, Vanessa, Gravel, Annie, Kaufer, Benedikt B., Flamand, Louis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394443/ https://www.ncbi.nlm.nih.gov/pubmed/32658923 http://dx.doi.org/10.1371/journal.ppat.1008683 |
Ejemplares similares
-
Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration
por: Gilbert-Girard, Shella, et al.
Publicado: (2020) -
RNF4 interacts with multiSUMOylated ETV4
por: Aguilar-Martinez, Elisa, et al.
Publicado: (2017) -
The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration
por: Wallaschek, Nina, et al.
Publicado: (2016) -
Characterization of human herpesvirus 6A/B U94 as ATPase, helicase, exonuclease and DNA-binding proteins
por: Trempe, Frédéric, et al.
Publicado: (2015) -
Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration
por: Wight, Darren J., et al.
Publicado: (2018)