Expression of type I collagen in response to Isoniazid exposure is indirect and is facilitated by collateral induction of cytochrome P450 2E1: An in-vitro study

We wanted to investigate whether Isoniazid (INH) can directly stimulate activation of hepatic stellate cells (HSCs) and enhance production of collagen. Treatment of human hepatic stellate cell line LX2 with or without 5μM INH for 24 to 72 hours was performed to look into content of cytochrome P450 2...

Descripción completa

Detalles Bibliográficos
Autores principales: Santra, Suman, Bishnu, Debasree, Dhali, Gopal Krishna, Santra, Amal, Chowdhury, Abhijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394448/
https://www.ncbi.nlm.nih.gov/pubmed/32735603
http://dx.doi.org/10.1371/journal.pone.0236992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394448/
https://www.ncbi.nlm.nih.gov/pubmed/32735603
http://dx.doi.org/10.1371/journal.pone.0236992

Ejemplares similares