Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles

When evaluating anti-cancer drugs, two different measurements are used: relative viability, which scores an amalgam of proliferative arrest and cell death, and fractional viability, which specifically scores the degree of cell killing. We quantify relationships between drug-induced growth inhibition...

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Detalles Bibliográficos
Autores principales: Schwartz, Hannah R., Richards, Ryan, Fontana, Rachel E., Joyce, Anna J., Honeywell, Megan E., Lee, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394473/
https://www.ncbi.nlm.nih.gov/pubmed/32579927
http://dx.doi.org/10.1016/j.celrep.2020.107800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394473/
https://www.ncbi.nlm.nih.gov/pubmed/32579927
http://dx.doi.org/10.1016/j.celrep.2020.107800

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