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Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles
When evaluating anti-cancer drugs, two different measurements are used: relative viability, which scores an amalgam of proliferative arrest and cell death, and fractional viability, which specifically scores the degree of cell killing. We quantify relationships between drug-induced growth inhibition...
Autores principales: | Schwartz, Hannah R., Richards, Ryan, Fontana, Rachel E., Joyce, Anna J., Honeywell, Megan E., Lee, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394473/ https://www.ncbi.nlm.nih.gov/pubmed/32579927 http://dx.doi.org/10.1016/j.celrep.2020.107800 |
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