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Liraglutide Attenuates Aβ42 Generation in APPswe/SH-SY5Y Cells Through the Regulation of Autophagy

OBJECTIVE: This study aimed to clarify whether liraglutide, a GLP-1 analogue, can ameliorate Aβ pathology through the regulation of autophagy in Alzheimer’s disease (AD) and to explore the related mechanisms thereof. METHODS: We used SH-SY5Y cells transiently transfected with APP695swe plasmid as an...

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Detalles Bibliográficos
Autores principales:	Kong, Jingjing, Wan, Liping, Wang, Yanfu, Zhang, Hua, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394597/ https://www.ncbi.nlm.nih.gov/pubmed/32801716 http://dx.doi.org/10.2147/NDT.S260160

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