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Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

BACKGROUND: Individuals of the same chronological age display different rates of biological ageing. A number of measures of biological age have been proposed which harness age-related changes in DNA methylation profiles. These measures include five ‘epigenetic clocks’ which provide an index of how m...

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Detalles Bibliográficos
Autores principales: Hillary, Robert F., Stevenson, Anna J., McCartney, Daniel L., Campbell, Archie, Walker, Rosie M., Howard, David M., Ritchie, Craig W., Horvath, Steve, Hayward, Caroline, McIntosh, Andrew M., Porteous, David J., Deary, Ian J., Evans, Kathryn L., Marioni, Riccardo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394682/
https://www.ncbi.nlm.nih.gov/pubmed/32736664
http://dx.doi.org/10.1186/s13148-020-00905-6