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A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E

New treatments for the diseases caused by apicomplexans are needed. Recently, we determined that tartrolon E (trtE), a secondary metabolite derived from a shipworm symbiotic bacterium, has broad-spectrum anti-apicomplexan parasite activity. TrtE inhibits apicomplexans at nM concentrations in vitro,...

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Detalles Bibliográficos
Autores principales: Bowden, Gregory D., Reis, Patricia M., Rogers, Maxwell B., Bone Relat, Rachel M., Brayton, Kelly A., Wilson, Sarah K., Di Genova, Bruno Martorelli, Knoll, Laura J., Nepveux V, Felix J., Tai, Albert K., Ramadhar, Timothy R., Clardy, Jon, O'Connor, Roberta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394737/
https://www.ncbi.nlm.nih.gov/pubmed/32738587
http://dx.doi.org/10.1016/j.ijpddr.2020.07.003