CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD). This hypothesis is strengthened by recent findings suggesting that oxytosis/ferropt...

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Detalles Bibliográficos
Autores principales: Ates, Gamze, Goldberg, Joshua, Currais, Antonio, Maher, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394765/
https://www.ncbi.nlm.nih.gov/pubmed/32863221
http://dx.doi.org/10.1016/j.redox.2020.101648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394765/
https://www.ncbi.nlm.nih.gov/pubmed/32863221
http://dx.doi.org/10.1016/j.redox.2020.101648

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