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Targeting Prostate Cancer Using Intratumoral Cytotopically Modified Interleukin-15 Immunotherapy in a Syngeneic Murine Model

BACKGROUND: The prostate cancer microenvironment is highly immunosuppressive; immune cells stimulated in the periphery by systemic immunotherapies will be rendered inactive once entering this environment. Immunotherapies for prostate cancer need to break this immune tolerance. We have previously ide...

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Detalles Bibliográficos
Autores principales: Papaevangelou, Efthymia, Smolarek, Dorota, Smith, Richard A, Dasgupta, Prokar, Galustian, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394845/
https://www.ncbi.nlm.nih.gov/pubmed/32802803
http://dx.doi.org/10.2147/ITT.S257443