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Filoviruses Use the HOPS Complex and UVRAG To Traffic to Niemann-Pick C1 Compartments during Viral Entry

Ebola virus (EBOV) entry requires internalization into host cells and extensive trafficking through the endolysosomal network in order to reach late endosomal/lysosomal compartments that contain triggering factors for viral membrane fusion. These triggering factors include low-pH-activated cellular...

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Detalles Bibliográficos
Autores principales: Bo, Yuxia, Qiu, Shirley, Mulloy, Rory P., Côté, Marceline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394885/
https://www.ncbi.nlm.nih.gov/pubmed/32493822
http://dx.doi.org/10.1128/JVI.01002-20