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Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila

Dopaminergic (DA) neurons have been implicated as key targets in neurological disorders, notably those involving locomotor impairment, and are considered to be highly vulnerable to mitochondrial dysfunction, a common feature of such diseases. Here we investigated a Drosophila model of locomotor diso...

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Detalles Bibliográficos
Autores principales: Yalgin, Cagri, Rovenko, Bohdana, Andjelković, Ana, Neefjes, Margot, Oymak, Burak, Dufour, Eric, Hietakangas, Ville, Jacobs, Howard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394922/
https://www.ncbi.nlm.nih.gov/pubmed/32738610
http://dx.doi.org/10.1016/j.isci.2020.101362