Big data, observational research and P-value: a recipe for false-positive findings? A study of simulated and real prospective cohorts

BACKGROUND: An increasing number of observational studies combine large sample sizes with low participation rates, which could lead to standard inference failing to control the false-discovery rate. We investigated if the ‘empirical calibration of P-value’ method (EPCV), reliant on negative controls...

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Detalles Bibliográficos
Autores principales: Veronesi, Giovanni, Grassi, Guido, Savelli, Giordano, Quatto, Piero, Zambon, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
P Values
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394945/
https://www.ncbi.nlm.nih.gov/pubmed/31620789
http://dx.doi.org/10.1093/ije/dyz206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394945/
https://www.ncbi.nlm.nih.gov/pubmed/31620789
http://dx.doi.org/10.1093/ije/dyz206

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