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Big data, observational research and P-value: a recipe for false-positive findings? A study of simulated and real prospective cohorts
BACKGROUND: An increasing number of observational studies combine large sample sizes with low participation rates, which could lead to standard inference failing to control the false-discovery rate. We investigated if the ‘empirical calibration of P-value’ method (EPCV), reliant on negative controls...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394945/ https://www.ncbi.nlm.nih.gov/pubmed/31620789 http://dx.doi.org/10.1093/ije/dyz206 |