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Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

BACKGROUND: Nearly a fifth of the world’s population suffer from migraine headache, yet risk factors for this disease are poorly characterized. METHODS: To further elucidate these factors, we conducted a genetic correlation analysis using cross-trait linkage disequilibrium (LD) score regression betw...

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Detalles Bibliográficos
Autores principales: Siewert, Katherine M, Klarin, Derek, Damrauer, Scott M, Chang, Kyong-Mi, Tsao, Philip S, Assimes, Themistocles L, Davey Smith, George, Voight, Benjamin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394956/
https://www.ncbi.nlm.nih.gov/pubmed/32306029
http://dx.doi.org/10.1093/ije/dyaa050