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Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens

While regulatory requirements for carcinogenicity testing of chemicals vary according to product sector and regulatory jurisdiction, the standard approach starts with a battery of genotoxicity tests (which include mutagenicity assays). If any of the in vivo genotoxicity tests are positive, a lifetim...

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Detalles Bibliográficos
Autores principales: Jacobs, Miriam N., Colacci, Annamaria, Corvi, Raffaella, Vaccari, Monica, Aguila, M. Cecilia, Corvaro, Marco, Delrue, Nathalie, Desaulniers, Daniel, Ertych, Norman, Jacobs, Abigail, Luijten, Mirjam, Madia, Federica, Nishikawa, Akiyoshi, Ogawa, Kumiko, Ohmori, Kiyomi, Paparella, Martin, Sharma, Anoop Kumar, Vasseur, Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395040/
https://www.ncbi.nlm.nih.gov/pubmed/32594184
http://dx.doi.org/10.1007/s00204-020-02784-5