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Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals

Evidence is mounting for the central role of mitochondrial dysfunction in several pathologies including metabolic diseases, accelerated ageing, neurodegenerative diseases and in certain xenobiotic-induced organ toxicity. Assessing mitochondrial perturbations is not trivial and the outcomes of such i...

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Detalles Bibliográficos
Autores principales: van der Stel, Wanda, Carta, Giada, Eakins, Julie, Darici, Salihanur, Delp, Johannes, Forsby, Anna, Bennekou, Susanne Hougaard, Gardner, Iain, Leist, Marcel, Danen, Erik H. J., Walker, Paul, van de Water, Bob, Jennings, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395062/
https://www.ncbi.nlm.nih.gov/pubmed/32607615
http://dx.doi.org/10.1007/s00204-020-02792-5