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Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol‐Related Liver Disease

Nicotinamide adenine dinucleotide (NAD(+)) and related coenzymes play critical roles in liver function. Although hepatic alcohol metabolism depresses NAD(+), current understanding of the NAD(+) metabolome in alcohol‐related liver disease (ArLD) is based on animal models. We used human liver samples...

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Detalles Bibliográficos
Autores principales: Parker, Richard, Schmidt, Mark S., Cain, Owen, Gunson, Bridget, Brenner, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395074/
https://www.ncbi.nlm.nih.gov/pubmed/32766477
http://dx.doi.org/10.1002/hep4.1530