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Synergistic drug combinations and machine learning for drug repurposing in chordoma

Chordoma is a devastating rare cancer that affects one in a million people. With a mean-survival of just 6 years and no approved medicines, the primary treatments are surgery and radiation. In order to speed new medicines to chordoma patients, a drug repurposing strategy represents an attractive app...

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Detalles Bibliográficos
Autores principales: Anderson, Edward, Havener, Tammy M., Zorn, Kimberley M., Foil, Daniel H., Lane, Thomas R., Capuzzi, Stephen J., Morris, Dave, Hickey, Anthony J., Drewry, David H., Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395084/
https://www.ncbi.nlm.nih.gov/pubmed/32737414
http://dx.doi.org/10.1038/s41598-020-70026-w