Crystal structure of the Rab33B/Atg16L1 effector complex

The Atg12-Atg5/Atg16L1 complex is recruited by WIPI2b to the site of autophagosome formation. Atg16L1 is an effector of the Golgi resident GTPase Rab33B. Here we identified a minimal stable complex of murine Rab33B(30–202) Q92L and Atg16L1(153–210). Atg16L1(153–210) comprises the C-terminal part of...

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Detalles Bibliográficos
Autores principales: Metje-Sprink, Janina, Groffmann, Johannes, Neumann, Piotr, Barg-Kues, Brigitte, Ficner, Ralf, Kühnel, Karin, Schalk, Amanda M., Binotti, Beyenech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395093/
https://www.ncbi.nlm.nih.gov/pubmed/32737358
http://dx.doi.org/10.1038/s41598-020-69637-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395093/
https://www.ncbi.nlm.nih.gov/pubmed/32737358
http://dx.doi.org/10.1038/s41598-020-69637-0

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