Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression

Aedes aegypti and Aedes albopictus mosquitoes are vectors of the RNA viruses chikungunya (CHIKV) and dengue that currently have no specific therapeutic treatments. The development of new methods to generate virus-refractory mosquitoes would be beneficial. Cas13b is an enzyme that uses RNA guides to...

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Detalles Bibliográficos
Autores principales: Tng, Priscilla Ying Lei, Carabajal Paladino, Leonela, Verkuijl, Sebald Alexander Nkosana, Purcell, Jessica, Merits, Andres, Leftwich, Philip Thomas, Fragkoudis, Rennos, Noad, Rob, Alphey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395101/
https://www.ncbi.nlm.nih.gov/pubmed/32737398
http://dx.doi.org/10.1038/s42003-020-01142-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395101/
https://www.ncbi.nlm.nih.gov/pubmed/32737398
http://dx.doi.org/10.1038/s42003-020-01142-6

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