Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases

Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically upon different mammalian proteomes. Hemorrhagic...

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Detalles Bibliográficos
Autores principales: Asega, Amanda F., Menezes, Milene C., Trevisan-Silva, Dilza, Cajado-Carvalho, Daniela, Bertholim, Luciana, Oliveira, Ana K., Zelanis, André, Serrano, Solange M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395112/
https://www.ncbi.nlm.nih.gov/pubmed/32737331
http://dx.doi.org/10.1038/s41598-020-69396-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395112/
https://www.ncbi.nlm.nih.gov/pubmed/32737331
http://dx.doi.org/10.1038/s41598-020-69396-y

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