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Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn’s disease

Deficiencies in methyl-donor molecules (folate, B12 vitamin), DNA methylation alteration and high prevalence of Adherent-Invasive Escherichia coli (AIEC) are frequently observed in Crohn’s disease (CD) patients. AIEC bacteria adhere to the enterocytes through abnormally expressed carcinoembryonic an...

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Detalles Bibliográficos
Autores principales: Gimier, Elodie, Chervy, Mélissa, Agus, Allison, Sivignon, Adeline, Billard, Elisabeth, Privat, Maud, Viala, Sandrine, Minet-Quinard, Régine, Buisson, Anthony, Vazeille, Emilie, Barnich, Nicolas, Denizot, Jérémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395125/
https://www.ncbi.nlm.nih.gov/pubmed/32737335
http://dx.doi.org/10.1038/s41598-020-69472-3