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Light microscopy of proteins in their ultrastructural context

Resolving the distribution of specific proteins at the nanoscale in the ultrastructural context of the cell is a major challenge in fluorescence microscopy. We report the discovery of a new principle for an optical contrast equivalent to electron microscopy (EM) which reveals the ultrastructural con...

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Detalles Bibliográficos
Autores principales: M’Saad, Ons, Bewersdorf, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395138/
https://www.ncbi.nlm.nih.gov/pubmed/32737322
http://dx.doi.org/10.1038/s41467-020-17523-8