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Visualizing drug binding interactions using microcrystal electron diffraction

Visualizing ligand binding interactions is important for structure-based drug design and fragment-based screening methods. Rapid and uniform soaking with potentially reduced lattice defects make small macromolecular crystals attractive targets for studying drug binding using microcrystal electron di...

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Detalles Bibliográficos
Autores principales: Clabbers, Max T. B., Fisher, S. Zoë, Coinçon, Mathieu, Zou, Xiaodong, Xu, Hongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395157/
https://www.ncbi.nlm.nih.gov/pubmed/32737395
http://dx.doi.org/10.1038/s42003-020-01155-1