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Visualizing drug binding interactions using microcrystal electron diffraction
Visualizing ligand binding interactions is important for structure-based drug design and fragment-based screening methods. Rapid and uniform soaking with potentially reduced lattice defects make small macromolecular crystals attractive targets for studying drug binding using microcrystal electron di...
Autores principales: | Clabbers, Max T. B., Fisher, S. Zoë, Coinçon, Mathieu, Zou, Xiaodong, Xu, Hongyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395157/ https://www.ncbi.nlm.nih.gov/pubmed/32737395 http://dx.doi.org/10.1038/s42003-020-01155-1 |
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