Control of protein palmitoylation by regulating substrate recruitment to a zDHHC-protein acyltransferase

Although palmitoylation regulates numerous cellular processes, as yet efforts to manipulate this post-translational modification for therapeutic gain have proved unsuccessful. The Na-pump accessory sub-unit phospholemman (PLM) is palmitoylated by zDHHC5. Here, we show that PLM palmitoylation is faci...

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Detalles Bibliográficos
Autores principales: Plain, Fiona, Howie, Jacqueline, Kennedy, Jennifer, Brown, Elaine, Shattock, Michael J., Fraser, Niall J., Fuller, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395175/
https://www.ncbi.nlm.nih.gov/pubmed/32737405
http://dx.doi.org/10.1038/s42003-020-01145-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395175/
https://www.ncbi.nlm.nih.gov/pubmed/32737405
http://dx.doi.org/10.1038/s42003-020-01145-3

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