Trastuzumab increases pulmonary vein arrhythmogenesis through modulating pulmonary vein electrical and conduction properties via phosphatidylinositol 3-kinase signaling

OBJECTIVE(S): Drug-induced atrial fibrillation (AF) is considered an adverse effect of chemotherapeutic drugs. AF is a crucial risk factor for stroke, heart failure, myocardial infarction, and mortality. Pulmonary veins (PVs) are considered triggers inducing AF, and the sinoatrial node (SAN) may mod...

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Detalles Bibliográficos
Autores principales: Chang, Jun-Hei, Cheng, Chen-Chuan, Lu, Yen-Yu, Chen, Yao-Chang, Chen, Shih-Ann, Chen, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395187/
https://www.ncbi.nlm.nih.gov/pubmed/32774807
http://dx.doi.org/10.22038/ijbms.2020.44651.10432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395187/
https://www.ncbi.nlm.nih.gov/pubmed/32774807
http://dx.doi.org/10.22038/ijbms.2020.44651.10432

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