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Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening

The global health emergency generated by coronavirus disease 2019 (COVID-19) has prompted the search for preventive and therapeutic treatments for its pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There are many potential targets for drug discovery and development to ta...

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Detalles Bibliográficos
Autores principales: Abian, Olga, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Reyburn, Hugh T., Rizzuti, Bruno, Velazquez-Campoy, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395220/
https://www.ncbi.nlm.nih.gov/pubmed/32745548
http://dx.doi.org/10.1016/j.ijbiomac.2020.07.235