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Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing the nuclear factor kappa B (NF-κB) signaling pathway

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has extensively and rapidly spread in the world, causing an outbreak of acute infectious pneumonia. However, no specific antiviral drugs or vaccines can be used. Phillyrin (KD-1), a representative ingredient of Forsythia suspen...

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Detalles Bibliográficos
Autores principales: Ma, Qinhai, Li, Runfeng, Pan, Weiqi, Huang, Wenbo, Liu, Bin, Xie, Yuqi, Wang, Zhoulang, Li, Chufang, Jiang, Haiming, Huang, Jicheng, Shi, Yongxia, Dai, Jun, Zheng, Kui, Li, Xiaobo, Hui, Min, Fu, Li, Yang, Zifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395229/
https://www.ncbi.nlm.nih.gov/pubmed/32890913
http://dx.doi.org/10.1016/j.phymed.2020.153296