A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

Aberrantly expressed cytokines in the bone marrow (BM) niche are increasingly recognized as critical mediators of survival and expansion of leukemic stem cells. To identify regulators of primitive chronic myeloid leukemia (CML) cells, we performed a high-content cytokine screen using primary CD34(+)...

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Detalles Bibliográficos
Autores principales: von Palffy, Sofia, Landberg, Niklas, Sandén, Carl, Zacharaki, Dimitra, Shah, Mansi, Nakamichi, Naoto, Hansen, Nils, Askmyr, Maria, Lilljebjörn, Henrik, Rissler, Marianne, Karlsson, Christine, Scheding, Stefan, Richter, Johan, Eaves, Connie J., Bhatia, Ravi, Järås, Marcus, Fioretos, Thoas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395258/
https://www.ncbi.nlm.nih.gov/pubmed/31582541
http://dx.doi.org/10.3324/haematol.2019.220434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395258/
https://www.ncbi.nlm.nih.gov/pubmed/31582541
http://dx.doi.org/10.3324/haematol.2019.220434

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