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A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells
Aberrantly expressed cytokines in the bone marrow (BM) niche are increasingly recognized as critical mediators of survival and expansion of leukemic stem cells. To identify regulators of primitive chronic myeloid leukemia (CML) cells, we performed a high-content cytokine screen using primary CD34(+)...
Autores principales: | von Palffy, Sofia, Landberg, Niklas, Sandén, Carl, Zacharaki, Dimitra, Shah, Mansi, Nakamichi, Naoto, Hansen, Nils, Askmyr, Maria, Lilljebjörn, Henrik, Rissler, Marianne, Karlsson, Christine, Scheding, Stefan, Richter, Johan, Eaves, Connie J., Bhatia, Ravi, Järås, Marcus, Fioretos, Thoas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395258/ https://www.ncbi.nlm.nih.gov/pubmed/31582541 http://dx.doi.org/10.3324/haematol.2019.220434 |
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