Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

Chronic inflammation is a key pathological hallmark of multiple sclerosis (MS) and suggests that resolution of inflammation, orchestrated by specialized pro-resolving lipid mediators (LM), is impaired. Here, through targeted-metabololipidomics in peripheral blood of patients with MS, we revealed tha...

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Detalles Bibliográficos
Autores principales: Kooij, Gijs, Troletti, Claudio Derada, Leuti, Alessandro, Norris, Paul C., Riley, Ian, Albanese, Maria, Ruggieri, Serena, Libreros, Stephania, van der Pol, Susanne M.A., van het Hof, Bert, Schell, Yoelle, Guerrera, Gisella, Buttari, Fabio, Mercuri, Nicola Biagio, Centonze, Diego, Gasperini, Claudio, Battistini, Luca, de Vries, Helga E., Serhan, Charles N., Chiurchiù, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395264/
https://www.ncbi.nlm.nih.gov/pubmed/31780628
http://dx.doi.org/10.3324/haematol.2019.219519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395264/
https://www.ncbi.nlm.nih.gov/pubmed/31780628
http://dx.doi.org/10.3324/haematol.2019.219519

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