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Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction
Chronic inflammation is a key pathological hallmark of multiple sclerosis (MS) and suggests that resolution of inflammation, orchestrated by specialized pro-resolving lipid mediators (LM), is impaired. Here, through targeted-metabololipidomics in peripheral blood of patients with MS, we revealed tha...
Autores principales: | Kooij, Gijs, Troletti, Claudio Derada, Leuti, Alessandro, Norris, Paul C., Riley, Ian, Albanese, Maria, Ruggieri, Serena, Libreros, Stephania, van der Pol, Susanne M.A., van het Hof, Bert, Schell, Yoelle, Guerrera, Gisella, Buttari, Fabio, Mercuri, Nicola Biagio, Centonze, Diego, Gasperini, Claudio, Battistini, Luca, de Vries, Helga E., Serhan, Charles N., Chiurchiù, Valerio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395264/ https://www.ncbi.nlm.nih.gov/pubmed/31780628 http://dx.doi.org/10.3324/haematol.2019.219519 |
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