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Transferrin receptor 1-mediated iron uptake plays an essential role in hematopoiesis

Transferrin receptor 1 (Tfr1) mediates the endocytosis of diferric transferrin in order to transport iron, and Tfr1 has been suggested to play an important role in hematopoiesis. To study the role of Tfr1 in hematopoiesis, we generated hematopoietic stem cell (HSC) specific Tfr1 knockout mice. We fo...

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Detalles Bibliográficos
Autores principales: Wang, Shufen, He, Xuyan, Wu, Qian, Jiang, Li, Chen, Liyun, Yu, Yingying, Zhang, Pan, Huang, Xin, Wang, Jia, Ju, Zhenyu, Min, Junxia, Wang, Fudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395265/
https://www.ncbi.nlm.nih.gov/pubmed/31601687
http://dx.doi.org/10.3324/haematol.2019.224899