Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance

Protection from acute lymphoblastic leukemia relapse in the central nervous system (CNS) is crucial to survival and quality of life for leukemia patients. Current CNS-directed therapies cause significant toxicities and are only partially effective. Moreover, the impact of the CNS microenvironment on...

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Detalles Bibliográficos
Autores principales: Jonart, Leslie M., Ebadi, Maryam, Basile, Patrick, Johnson, Kimberly, Makori, Jessica, Gordon, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395284/
https://www.ncbi.nlm.nih.gov/pubmed/31624109
http://dx.doi.org/10.3324/haematol.2019.230334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395284/
https://www.ncbi.nlm.nih.gov/pubmed/31624109
http://dx.doi.org/10.3324/haematol.2019.230334

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