Cargando…

Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance

Protection from acute lymphoblastic leukemia relapse in the central nervous system (CNS) is crucial to survival and quality of life for leukemia patients. Current CNS-directed therapies cause significant toxicities and are only partially effective. Moreover, the impact of the CNS microenvironment on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jonart, Leslie M., Ebadi, Maryam, Basile, Patrick, Johnson, Kimberly, Makori, Jessica, Gordon, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395284/ https://www.ncbi.nlm.nih.gov/pubmed/31624109 http://dx.doi.org/10.3324/haematol.2019.230334

Ejemplares similares

CD99 antibody disrupts T-cell acute lymphoblastic leukemia adhesion to meningeal cells and attenuates chemoresistance
por: Ebadi, Maryam, et al.
Publicado: (2021)

Leukemia-on-a-chip: Dissecting the chemoresistance mechanisms in B cell acute lymphoblastic leukemia bone marrow niche
por: Ma, Chao, et al.
Publicado: (2020)

Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
por: Kouzi, Farah, et al.
Publicado: (2019)

Integrin-Mediated Adhesion and Chemoresistance of Acute Lymphoblastic Leukemia Cells Residing in the Bone Marrow or the Central Nervous System
por: Scharff, Bibi Fatima Syed Shah, et al.
Publicado: (2020)

Correction: Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
por: Kouzi, Farah, et al.
Publicado: (2019)

The Role of the Central Nervous System Microenvironment in Pediatric Acute Lymphoblastic Leukemia
por: Gossai, Nathan P., et al.
Publicado: (2017)

Gap Junctions in the Bone Marrow Lympho-Hematopoietic Stem Cell Niche, Leukemia Progression, and Chemoresistance
por: Singh, Abhishek K., et al.
Publicado: (2020)

Central Nervous System Double Relapse of Acute Promyelocytic Leukemia and Acute Myelomonocytic Leukemia
por: Stanko, Laura M., et al.
Publicado: (2019)

Role of SIRT1 in Chemoresistant Leukemia
por: Fajardo-Orduña, Guadalupe Rosario, et al.
Publicado: (2023)

Lysosome-mediated chemoresistance in acute myeloid leukemia
por: Cuesta-Casanovas, Laia, et al.
Publicado: (2022)

Central Nervous System Prophylaxis and Treatment in Acute Leukemias
por: Wu, Susan Y., et al.
Publicado: (2022)

Diagnosis and management of adult central nervous system leukemia
por: Liu, Siyu, et al.
Publicado: (2023)

Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?
por: Vaisitti, Tiziana, et al.
Publicado: (2018)

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance
por: Barbier, Valerie, et al.
Publicado: (2020)

Isolated Central Nervous System Relapse of Acute Lymphoblastic Leukemia
por: Sung, Sang-Hyun, et al.
Publicado: (2014)

Isolated Central Nervous System Relapse in Chronic Myeloid Leukemia
por: Gomez, Juliana, et al.
Publicado: (2015)

Central nervous system involvement in patients with acute myeloid leukemia
por: YAŞAR, Hatime Arzu, et al.
Publicado: (2021)

Functional Integration of Acute Myeloid Leukemia into the Vascular Niche
por: Cogle, Christopher R., et al.
Publicado: (2014)

A narrative review of central nervous system involvement in acute leukemias
por: Deak, Dalma, et al.
Publicado: (2021)

Prognostic factors for clinical outcomes of patients with central nervous system leukemia
por: Bharucha, Jinai, et al.
Publicado: (2020)

Central nervous system therapy in acute lymphoblastic leukemia: no more, no less
por: Rives, Susana
Publicado: (2023)

Chronic myeloid leukemia extramedullary blast crisis presenting as central nervous system leukemia: A case report
por: Jin, Mingwei, et al.
Publicado: (2018)

Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia
por: Hicks, Chindo, et al.
Publicado: (2016)

Leukostasis With Isolated Central Nervous System Involvement in Chronic Phase of Chronic Myelogenous Leukemia
por: Jeon, Won Jin, et al.
Publicado: (2023)

The Instructive Role of the Bone Marrow Niche in Aging and Leukemia
por: Lazzari, Elisa, et al.
Publicado: (2018)

The hematopoietic stem-cell niche in health and leukemia
por: Sánchez-Aguilera, Abel, et al.
Publicado: (2016)

Transcriptomic profile of intrinsically chemoresistant acute myeloid leukemia patients
por: Horibata, Sachi
Publicado: (2019)

Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia
por: Alakel, Nael, et al.
Publicado: (2017)

Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia
por: Tager, Dany, et al.
Publicado: (2017)

Central nervous system involvement of acute promyelocytic leukemia, three case reports
por: Furuya, Aya, et al.
Publicado: (2017)

Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions
por: Thastrup, Maria, et al.
Publicado: (2022)

Integrins and the Metastasis-like Dissemination of Acute Lymphoblastic Leukemia to the Central Nervous System
por: Modvig, Signe, et al.
Publicado: (2023)

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
por: Ariës, Ingrid M., et al.
Publicado: (2018)

The Bone Marrow Niche in B-Cell Acute Lymphoblastic Leukemia: The Role of Microenvironment from Pre-Leukemia to Overt Leukemia
por: Dander, Erica, et al.
Publicado: (2021)

Oxidative Stress and ROS-Mediated Signaling in Leukemia: Novel Promising Perspectives to Eradicate Chemoresistant Cells in Myeloid Leukemia
por: Trombetti, Silvia, et al.
Publicado: (2021)

Intra‐heterogeneity in transcription and chemoresistant property of leukemia‐initiating cells in murine Setd2(−/−) acute myeloid leukemia
por: Song, Jiachun, et al.
Publicado: (2021)

Stem cell niche as a prognostic factor in leukemia
por: Lee, Ga-Young, et al.
Publicado: (2015)

Targeting Leukemia Stem Cells in the Bone Marrow Niche
por: Tasian, Sarah K., et al.
Publicado: (2018)

Remodeling of Bone Marrow Niches and Roles of Exosomes in Leukemia
por: Yamaguchi, Takanori, et al.
Publicado: (2021)

Tumor Microenvironment in Acute Myeloid Leukemia: Adjusting Niches
por: Menter, Thomas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ckogctt8i1tb6sfbom1l3gb2uh