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Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding

Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in the bone marrow, differentiated from hematopoietic stem cells are generally considered as a uniform source of platelets. However, recent insi...

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Detalles Bibliográficos
Autores principales: Veninga, Alicia, De Simone, Ilaria, Heemskerk, Johan W.M., Cate, Hugo ten, van der Meijden, Paola E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395290/
https://www.ncbi.nlm.nih.gov/pubmed/32554558
http://dx.doi.org/10.3324/haematol.2019.235994