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Efficacy of JAK inhibitors in Crohn’s Disease

Inhibition of Janus kinases [JAKs] in Crohn’s disease [CD] patients has shown conflicting results in clinical trials. Tofacitinib, a pan-JAK inhibitor, showed efficacy in ulcerative colitis [UC] and has been approved for the treatment of patients with moderate to severe UC. In contrast, studies in C...

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Detalles Bibliográficos
Autor principal: Rogler, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395306/
https://www.ncbi.nlm.nih.gov/pubmed/31781755
http://dx.doi.org/10.1093/ecco-jcc/jjz186