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Molecular Structure and Function of Janus Kinases: Implications for the Development of Inhibitors
Cytokines can trigger multiple signalling pathways, including Janus tyrosine kinases [JAK] and signal transducers and activators of transcription [STATS] pathways. JAKs are cytoplasmic proteins that, following the binding of cytokines to their receptors, transduce the signal by phosphorylating STAT...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395311/ https://www.ncbi.nlm.nih.gov/pubmed/32083640 http://dx.doi.org/10.1093/ecco-jcc/jjz206 |